Assoc. Prof. Dr. Duygu Ege

Visiting Researcher (Boğaziçi University, Turkey), Alexander von Humboldt Foundation Fellow

Effect of bioactive glasses on soft tissue engineering

 

For healing soft tissues, borate bioactive glasses are exploited as they have been shown to reduce inflammation, induce angiogenesis and enable tissue attachment [1]. In fact, certain formulations of borate bioactive glasses have higher capacity to heal soft tissue than silicate glasses [2]. In this project, borate bioactive glasses are incorporated in a polymeric matrix and electrospun nanofibers are produced [1]. Various biologically active ions will be also doped in borate bioactive glasses and their effect on soft tissue regeneration will be determined by cell culture techniques.

 

[1] Kargozar S, Mozafari M, Ghenaatgar-Kasbi M and Baino F 2020 Bioactive glasses and glass/polymer composites for neuroregeneration: Should we be hopeful? Appl. Sci. 10 3421–41

[2] Ege D, Zheng K and Boccaccini A R 2022 Borate Bioactive Glasses (BBG): Bone Regeneration, Wound Healing Applications, and Future Directions ACS Appl. Bio Mater. 5 3608–22