Can Sinsoysal

Masterstudent

Electrophoretic deposition of bioactive and antibacterial coatings on metallic surfaces for drug delivery applications

 

Supervisors: Zoya Hadzhieva, Prof. Aldo R. Boccaccini

Electrophoretic deposition (EPD) is a method that can be rapidly employed to produce bioactive coatings on suitable surfaces such as biocompatible metals [1]. It can be used to provide antibacterial and cell-growth-inducing properties to metallic implants by creating depositions based on bioactive materials, biopolymers and phytotherapeutic drugs [1,2]. Such multicomponent bioactive coatings can yield advantages against infections, adverse reactions and poor integration of tissue to the implant [2]. This work will follow a multi-layered analysis of different potential coating agents to determine the optimal coating properties in terms of morphology, chemical composition, degradation behavior, bioactivity, cytocompatibility and antibacterial performance.

[1] Boccaccini, A. R., et al. “Electrophoretic deposition of biomaterials.” Journal of the Royal Society Interface 7.suppl_5 (2010): S581-S613.

[2] Bakhshandeh, S., and Saber Amin Yavari. “Electrophoretic deposition: a versatile tool against biomaterial associated infections.” Journal of Materials Chemistry B 6.8 (2018): 1128-1148.