Daniel Schembera

Master student

Hydrogel Composites Incorporating Bioactive Glass Particles for Wound Healing

 

Supervisors: Dr. Kai Zheng, Prof. Dr.-Ing. Aldo R. Boccaccini

Mesoporous bioactive glass micro- and nanospheres (PBGSs) have favorable properties for medical applications. As bioactive fillers in composites, PBGSs can carry and release drugs and biologically active ions to enhance the biological properties of matrices [1]. Due to these characteristics, PBGSs are attracting growing interest in soft tissue regeneration applications like skin repair or wound healing [2]. In this work, the incorporation of PBGSs into hydrogels for the fabrication of nanocomposite wound dressings will be studied. The morphology, physiochemical, mechanical and biological properties of the new composite hydrogels will be investigated.

[1] Zhu, H., et al., Multi-Functional Silica-Based Mesoporous Materials for Simultaneous Delivery of Biologically Active Ions and Therapeutic Biomolecules, Acta Biomater. 2021, in press.

[2] Zheng, K., et al., Porous bioactive glass micro- and nanospheres with controlled morphology: developments, properties and emerging biomedical applications. Materials Horizons 2021, 8, 300