Verena Piehler

Bachelor student

Bioactive glass-based scaffolds coated with nanoparticles for bone tissue engineering

 

Supervisors: Marcela Arango-Ospina, Prof. Dr.-Ing. habil. Aldo R. Boccaccini

Bioactive glass has been considered an interesting material in bone tissue engineering due to its biodegradability, bioactivity and its ability to promote bone regeneration during the dissolution process, based on the stimulation at the genetic level of bone forming cells [1]. In this project scaffolds will be fabricated using ICIE16 bioactive glass [2] and different variants of this glass with boron. The scaffolds will be coated with copper containing bioactive glass nanoparticles. The aim of this Bachelor theses is to characterize the scaffolds in terms of their bioactive behavior and mechanical properties. Similarly, the influence of boron and copper nanoparticles on scaffold bioactivity will be determined.

[1] Jones, J.R., Brauer, D.S., Hupa, L. and Greenspan, D.C. (2016), “Bioglass and Bioactive Glasses and Their Impact on Healthcare”. Int J Appl Glass Sci, 7: 423-434.

[2] Elgayar, I., et al. “Structural analysis of bioactive glasses.” Journal of Non-Crystalline Solids 351.2 (2005): 173-183.