Dr.-Ing. Kai Zheng

Dr.-Ing. Kai Zheng

2017 – 2021: Post Doc

Processing, characterisation and applications of multifunctional mesoporous bioactive glass nanoparticles

Supervisor: Prof. Dr.-Ing. habil. Aldo R. Boccaccini

My main research project involves the development of smart platforms for effective, non-invasive, and highly targeted therapies to treat delayed bone healing and non-healing chronic skin wounds. For this purpose, solid and hollow mesoporous bioactive glass nanoparticles (MBGN) are being developed for controlled delivery of therapeutic agents [1]. Specific bioactive ions that can promote osteogenesis, angiogenesis and with antibacterial potential are bein considered to dope these MBGN to enhance bone regeneration or wound healing [2]. The project is being carried out in the framework of the EU funded project (“MOZART”) “MesopOrous matrices for localiZed pH-triggered releAse of theRapeuTic ions and drugs” (LINK: http://www.mozartproject.eu/).

[1] K. Zheng, A.R. Boccaccini, Sol-gel processing of bioactive glass nanoparticles: A review, Adv. Colloid Interface Sci. (2017) In Press.

[2] A. Hoppe, N.S. Güldal, A.R. Boccaccini, A review of the biological response to ionic dissolution products from bioactive glasses and glass-ceramics., Biomaterials. 32 (2011) 2757–2774.

 

Zeitraum: 2013 – 2017

Thema / Repräsentative Veröffentlichung:

Bioactive glass scaffolds incorporating ion release function for enhaced bone formation

K. Zheng, et al., Timing of calcium nitrate addition affects morphology, dispersity and composition of bioactive glass nanoparticles, RSC Advances 6 (2016) 95101-95111.

weitere Informationen: Zur Zeit: PostDoc am Lehrstuhl  Biomaterialien, Universität Erlangen-Nürnberg

 

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